Peritoneal dialysis
Conditions
Interventions
Control group:The stable dialysis period is 12 to 16 weeks, and the conventional treatment lasts for 3 months
Fushen Granule Group:The stable dialysis period exceeded 12 to 16 weeks, with conventional treatment combined with oral administration of Fushen Granules for 3 months
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Informed Consent: Participants must provide signed informed consent and cooperate with the study procedures. 2. Age Requirement: Aged 18–80 years. 3. Diagnosis: Diagnosed with end-stage renal disease (ESRD) according to the 2012 KDIGO Clinical Practice Guidelines for CKD Evaluation and Management. 4. Dialysis Protocol: - Underwent peritoneal dialysis catheterization at our hospital. - Received regular follow-up at our peritoneal dialysis center. - Maintained stable peritoneal dialysis for 12–14 weeks. 5. Data Completeness: Participants must have complete clinical records and be able to undergo study-related statistical analysis. 6. Medication Restrictio: No use of **traditional Chinese medicine (TCM) or proprietary Chinese patent drugs within 2 weeks** prior to enrollment. 7. TCM Syndrome Pattern**: Classified as spleen-kidney qi deficiency syndrome.
Exclusion criteria
Exclusion criteria: 1. Unstable Medical Conditions: Patients with uncontrolled chronic diseases (e.g. severe cardiac cerebral hepatic or gastrointestinal disorders) malignancies hematologic diseases or active severe infections. 2. Concurrent Renal Replacement Therapy: Patients receiving hemodialysis or those who underwent hemodialysis plasmapheresis or hemofiltration within the past 12 weeks. 3. Cognitive/Behavioral Impairment: Patients with mental/psychological conditions that may compromise study compliance. 4. Peritoneal Dialysis-Associated Peritonitis: Active or recent episodes. 5. Pregnancy/Lactation: Women who are pregnant or breastfeeding. 6. Recent Medication Use: - Probiotics/microecological modulators antibiotics or immunosuppressants within 2 weeks. 7. Recent Abdominal Interventions: - Abdominal trauma gastrointestinal endoscopy or any surgery (other than peritoneal dialysis catheterization) within 12 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kidney Disease Treatment Acceptance Scale Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 36-Item Short Form Health Survey Score; | — |
Countries
China
Contacts
Public ContactChen Jiang
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed