colorectal cancer
Conditions
Interventions
Exposure group:Combined with Western medical treatment, patients received at least 3 months of stage-based Chinese medical treatment.
Non-exposure group:Receiving standard-of-care Western medical treatment
Sponsors
Xi yuan Hospital of CACMS
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Study Participants (1)Age =18 years old(2)Pathologically diagnosed with metastatic colon and rectal cancer and classified as Clinical Stage IV. (3)No restriction on treatment phase (e.g. first-line second-line or salvage therapy(4)ECOG Performance Status 0-2(5) Expected survival =3 months(6)Measurable lesions meetingRECIST 1.1 criteria(7)No severe cardiovascular respiratory hepatic or renal dysfunction (e.g. left ventricular ejection fraction =50% Child-Pugh score =7 CrCl =30 mL/min)(8)Normal coagulation function (e.g. PT/APTT within normal range) and no active bleeding orthrombotic disorders(9)Capable of adhering to the protocol for follow-up evaluations of efficacy and adverse reactions.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Study Participants (1)Patients with clinical manifestations of brain metastases;(2)Patients with concurrent that have not been fully treat ed; (3)Patients with defective mismatch repair (dMMR) as confirmed by immunohistochemistry or microsatellite instability-high (MSI-H) status verified by genetic testing;(4)Patients whose general medical condition render them unsuitable for conventional Western anti-tumor therapy;(5)Patients planning to participate or currently participating in other clinical trials;(6)Patients with conditions deemed unsuitable for inclusion by researchers such as pregnancy;(7)Patients whose medical records document a prior refusal to use their case for research purposes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| maintenance progression free survival; Annual OS rates;Disease Duration Control;Lines of Therapy;Disease Control Rate;Time of TCM intervention; | — |
Countries
China
Contacts
Public ContactZhang Tong
Xi yuan Hospital of CACMS
Outcome results
None listed