Sepsis
Conditions
Interventions
ontrol group:Conventional Western Medicine Treatment
Treatment group:200ml of the intestinal Tiaochangfang decoction for enema + conventional Western medicine treatment
Sponsors
Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1)Age between 18 and 80 years old gender not limited; 2) It conforms to the internationally recognized diagnostic criteria for SEPSIS (SEPSIS 3.0).
Exclusion criteria
Exclusion criteria: 1) Severe primary diseases that affect survival include: uncontrolled malignant tumors with multiple metastases that cannot be resected blood diseases and HIV etc. 2) Patients with liver or kidney dysfunction whose SOFA score for either the liver or kidney is =3 points; 3) Those who have continuously used immunosuppressants or received organ transplants within the past six months; 4) Those who have participated in other clinical trials within 30 days; 5) Have undergone major surgery or suffered significant trauma within the recent period (within one month); 6) Pregnant and lactating women; 7)The condition is severe (SOFA=15 or APACHE II=30) and/or the patient refuses active treatment; Patients with a history of allergy or contraindications to the ingredients of the intestinal-regulating formula used in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day case fatality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The types and abundance of intestinal flora;IL-6;IL-17;Treg/Th17;Metabolites of intestinal flora;IL-10; | — |
Countries
China
Contacts
Public ContactSu He
Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine
Outcome results
None listed