Hepatocellular Carcinoma,Gallbladder Cancer,Pancreatic Cancers
Conditions
Interventions
Experimental group:Abdominal radiotherapy+Bupi Yichang Pills
Control group:Abdominal radiotherapy
Sponsors
The first affiliated hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: 18-75 years old 2: Meets the indication of radiotherapy 3: ECOG score 0-1 4: Liver function grade Child-Pugh 5-7 5: Blood, liver and kidney function meet the following conditions: a) Neutrophil count =1.5×109/L b) Platelet count =75×109/L c) hemoglobin concentration =90g/L d) serum albumin concentration =30g/L e) total bilirubin =50umol/L f) AST and ALT were less than 5 times the upper limit of normal, ALP less than 4 times the upper normal limit g) International normalized ratio =2.3 h) creatinine less than 1.5 times the upper normal limit 6: Sign informed consent for clinical trials
Exclusion criteria
Exclusion criteria: 1: with other malignancies or had other malignancies within 5 years prior to enrollment 2: A history of thoracic and abdominal radiation therapy 3: Pregnant or lactating women or subjects who planned to have a family within two years 4: Severe cardiac, renal, and other organ dysfunction, such as arrhythmia (requiring medication or pacemaker installation), uncontrollable hypertension, history of myocardial infarction within 6 months, QT interval extension exceeding 450ms, congestive heart failure>NYHA level 2 5: Unable to take oral medication 6: Informed consent or inability to cooperate may be affected by other serious medical conditions, such as alcoholism, drug abuse or mental illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastrointestinal reactions;Bone marrow suppression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment completion rate;Immunomodulatory status; Quality of Life; | — |
Countries
China
Contacts
Public ContactLiu Jiahui
The first affiliated hospital, Sun Yat-sen University
Outcome results
None listed