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Clinical study on the efficacy and safety of Shefan lotion in treating high-risk HPV infection (damp-heat downward syndrome)

Clinical study on the efficacy and safety of Shefan lotion in treating high-risk HPV infection (damp-heat downward syndrome)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001645
Enrollment
Unknown
Registered
2025-09-01
Start date
2025-09-08
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HPV infection

Interventions

Shefan lotion (test group):Smoke and wash with snake alum lotion for 3-5 minutes
blank control group:Blank control group: No medication was used and free consultation was provided.
Funing *l expansion suppository (positive control drug group):Funing Vaginal Expanding Suppository: Insert one suppository into the vagina twice daily, morning and evening.

Sponsors

Xiyuan HospitalChina Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the Western medicine diagnostic criteria for high-risk HPV infection; 2. Comply with the traditional Chinese medicine diagnostic criteria for leukorrhagia/*l itching/*l sores and damp-heat downward flow syndrome; 3. Female aged 18 to 65 years old having * life; 4. Those with normal cognitive function no obvious disturbance of consciousness and a correct description of the condition:5. Those who voluntarily participated and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. A history of acute pelvic inflammatory disease lower genital tract and perianal eczema in the past 1 month: 2. Women preparing for pregnancy pregnant or nursing; 3. Taking antibiotics and vaginitis treatment drugs in the past 1 month: 4. Place a tail wire intrauterine device; 5. Allergic constitution or allergies to multiple drugs especially those with a history of local skin and mucous membrane allergies; 6. Patients with severe diseases such as respiratory digestive circulation nervous and blood systems: 7. Histopathological examination diagnosed with HSI or above

Design outcomes

Primary

MeasureTime frame
HPV negative rate;

Secondary

MeasureTime frame
Changes in TCM syndrome scores;Pathological reversal rate;VMB(vaginal microbiota, VMB);Cervical cytology indicators (TCT);

Countries

china

Contacts

Public Contactkun ma

Xiyuan HospitalChina Academy of Chinese Medical Sciences

makun20210202@163.com13910218105

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026