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Study on the Pathogenesis of Emaciation in Populations with Asthenic Constitution Based on the Gut-Muscle Axis.

Study on the Pathogenesis of Emaciation in Populations with Asthenic Constitution Based on the Gut-Muscle Axis.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025001622
Enrollment
Unknown
Registered
2025-08-28
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emaciation

Interventions

control group:none
Observation group:none

Sponsors

Zhongshan Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of simple wasting: excluding common secondary causes of wasting such as malignant tumors tuberculosis diabetes and hyperthyroidism and body mass index (BMI) < 18.5kg/m2. 2. aged from 18 to 60 years old. 3.signed informed consent. 4.The constitution was determined by the Constitution Classification and Determination of Traditional Chinese Medicine (CCMQ) issued by the Chinese Association of Traditional Chinese Medicine in March 2009. According to the CCMQ the patients were judged as deficiency constitution (including qi deficiency constitution Yang deficiency constitution and Yin deficiency constitution) or mild constitution.

Exclusion criteria

Exclusion criteria: 1) Those with mental disorders and severe communication disorders who are unable to complete the "Traditional Chinese Medicine Constitution Scale" and the testing process. 2) Pregnant or lactating women. 3) Weight-loss drugs that are prone to cause diarrhea during the acute attack period of gastroenteritis. 4) The patient had taken antibiotics or probiotics and other drugs that affect the intestinal flora in the three months prior to specimen collection.

Design outcomes

Primary

MeasureTime frame
Untargeted Metabolomic Analysis;Gut Microbiota;

Secondary

MeasureTime frame
Short Physical Performance Battery;Appendicular Skeletal Muscle Mass Index;

Countries

China

Contacts

Public ContactDENG Qian

Zhongshan Hospital of Traditional Chinese Medicine

glbblg@126.com13925327277

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026