Recurrent Spontaneous Abortion
Conditions
Interventions
control group:The control group received conventional Western medicine treatment according to the "Expert Consensus on the Diagnosis and Treatment of Recurrent Miscarriage" formulated by the Obstetric
2) Aspirin enteric coated tablets were taken daily at 25-75 mg/day
Endocrine disorders can be treated with Dexmedetomidine tablets, with a dosage of 10 mg orally, 3 times a day, etc.
Treatment group:On the basis of treatment in the control group, self formulated traditional Chinese medicine formulas for strengthening the spleen and benefiting the kidneys were taken for treatment.
Sponsors
Chengdu Women's and Children's Central Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Meets the RSA Western medicine diagnostic criteria and the traditional Chinese medicine syndrome diagnostic criteria for spleen kidney deficiency, and conducts pregnancy diagnosis according to the Western medicine pregnancy diagnostic criteria; (2) Married women aged 20-40 years old; (3) Willing to take traditional Chinese medicine orally for treatment; (4) Understand the content of this experiment, voluntarily participate, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Combining autoimmune diseases or receiving immunotherapy (2) Detecting chromosomal karyotype abnormalities in couples (3) Antibiotics and microbial preparations taken within 4 weeks prior to specimen collection (4) B-ultrasound examination of uterine malformations (such as unicornuate uterus, mediastinal uterus) (5) Patients with severe mental illnesses, including heart, liver, kidney, and other systemic diseases (6) Ectopic pregnancy and molar pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fetal survival rate ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Transforming growth factor -ß;estradiol;The diversity, richness, and specific changes of gut microbiota;progesterone;ß - human chorionic gonadotropin; interleukin-17;interleukin-6;interleukin-10;Non targeted metabolites in feces; | — |
Countries
China
Contacts
Public ContactZhou xiaoling
Chengdu Women's and Children's Central Hospital
Outcome results
None listed