Late Life Depression
Conditions
Interventions
Late Life Depression:Routine antidepressant treatment in clinical practice
Sponsors
Shandong Mental Health Center
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients with Late Life Depression: Enrollment Criteria: Age=60 years; Han nationality male or female right-handed. Meets International Classification of Diseases (ICD) 10th edition At least one depressive episode at age 60 and later. Currently in a depressive episode (Hamilton Depression Rating Scale [17 items] score >17). No systemic antidepressant therapy in the 2 weeks prior to enrollment and no Modified Electra convulsive therapy (MECT) therapy in the past 3 months. Normal control: Enrollment Criteria: Age=60 years; No current or previous history of psychiatric illness.
Exclusion criteria
Exclusion criteria: Patients with Late Life Depression: Exclusion Criteria: Depression secondary to organic lesions or other psychiatric disorders; Those who are unable to cooperate such as serious violent attacks or suicidal behavior; Patients with mental retardation dementia epilepsy and end-stage disease. Normal control: Exclusion Criteria: Severe medical illness somatic illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The score reduction rate of the Hamilton Depression Rating Scale;The patient's remission status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function;Markers of inflammation;Indicators of brain function;Quality of life;Drug side effects; | — |
Countries
China
Contacts
Public ContactMiao Qi
Shandong Mental Health Center
Outcome results
None listed