The aging condition of middle-aged and elderly people
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age range: 45 to 80 years old; (2) Have signed the informed consent form and be capable of completing the entire experimental process; (3) For the Tai Chi group the participants should have practiced for more than one year and maintained regular exercise in related activities (at least three times a week each session lasting at least one hour).
Exclusion criteria
Exclusion criteria: (1) Those with severe disorders of the musculoskeletal nervous and cardiopulmonary systems; (2) Those who have undergone implant surgery or have metal implants in their bodies; (3) Those with significant visual or auditory impairments or disorders or who cannot understand and communicate normally which would affect the assessment; (4) Those with movement disorders who cannot fully participate in the entire experimental process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density;Pulse Wave Velocity;bone resorption markers;bone formation markers;Skeletal muscle mass;Bone turnover markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vascular Aging;Short Physical Performance Battery;Pittsburgh Sleepiness Scale;Hormones and related proteins;Synovial fluid markers;inflammatory response;Muscle Physical Properties Test;Questionnaire on Quality of Life for Lower Extremity Arteriosclerosis Obliterans;skeletal aging;Epigenetic regulation;oxidative stress;International Physical Activity Questionnaire;Calcium ion and its regulatory proteins;Vascular endothelial function indicators;quantification test of sensory and motor neurode;Cerebral oxygen parameter;ankle-brachial index;Neuroendocrine indicators;Neurotransmitter;Quality of Life Scale (SF-36);Nutrition scale;Exercise capacity;kinematics and kinetics related parameters;Brain aging;Stress Perception Scale (CPSS);Activities of daily living;Cognitive scale;Vascular Aging Questionnaire;Seattle Angina Questionnaire;gut microbiota;Depression Scale;intestinal barrier function;miRNA;Matrix proteins;heart rate variability;Balance ability;Anxiety Scale;Urine markers Glucosyl-galact; | — |
Countries
China
Contacts
Beijing Normal University