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The mechanism and clinical validation of Suv39h1 in mediating primary osteoporosis of kidney-yang deficiency type and osteoporotic fractures

The mechanism and clinical validation of Suv39h1 in mediating primary osteoporosis of kidney-yang deficiency type and osteoporotic fractures

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025001595
Enrollment
Unknown
Registered
2025-08-21
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Osteoporosis of Kidney-Yang Deficiency Type and Osteoporotic Fracture of Kidney-Yang Deficiency Type

Interventions

Non-renal yang deficiency type primary osteoporosis:Non
Renal Yang Deficiency Type Primary Osteoporotic Fracture:Non
Non-Renal Yang Deficiency Type Primary Osteoporotic Fracture:None
Renal Yang Deficiency Type Primary Osteoporosis:Non

Sponsors

Gansu Provincial Hospital of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 79 Years

Inclusion criteria

Inclusion criteria: Meet the diagnostic criteria of "osteoporosis" or "osteoporotic intertrochanteric fracture of the femur"; Male and female patients aged between 40 and 80 years old; Sign the informed consent form and ensure compliance with the trial.

Exclusion criteria

Exclusion criteria: Open fractures with soft tissue defects or infected individuals; Those with other heart brain lung kidney and other diseases that threaten life; Those with poor physical condition who are difficult to undergo surgery; Suffering from other secondary osteoporosis diseases (such as diabetes long-term use of hormones etc.).

Design outcomes

Primary

MeasureTime frame
Western Blot;

Secondary

MeasureTime frame
Metabolomics sequencing;Transcriptome level;Single-cell transcriptome sequencing;Proteome level;

Countries

China

Contacts

Public ContactJin Huang

Gansu Provincial Hospital of TCM

zht1997zht@163.com+86 198 1194 0964

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026