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The clinical efficacy and mechanism of Zhitong Shengji Powder in the treatment of chronic skin ulcers: A prospective randomized controlled study

The clinical efficacy and mechanism of Zhitong Shengji Powder in the treatment of chronic skin ulcers: A prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001547
Enrollment
Unknown
Registered
2025-08-09
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic skin ulcers

Interventions

Control group:External application of physiological saline combined with Xiangpi Shengji Gao
Treatment group:External application of Zhitong Shengji Powder combined with Xiangpi Shengji Ointment

Sponsors

The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1)Wounds caused by various reasons that have not healed for more than one month; (2) Aged between 18 and 75; (3) The wound area is larger than 3×3cm (4) Voluntarily cooperate with the observation and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Ulcerative wounds located on the head and face perineum or severely infected wounds; (2) Patients with severe diseases such as cardiovascular cerebrovascular liver kidney and blood system disorders or mental illness; (3) Patients whose wound size cannot obtain satisfactory pathological tissue specimens; (4) Pregnant or lactating patients; (5) Patients with special ulcers such as syrutic ulcers cancerous ulcers or tuberculous ulcers; (6) Those who are allergic to the ingredients of traditional Chinese medicine for external use. (7) No topical medications containing growth factors have been used in the past week.

Design outcomes

Primary

MeasureTime frame
Change in wound area;

Secondary

MeasureTime frame
Visual Analogue Scale (VAS) pain score;

Countries

China

Contacts

Public ContactLinlin LI

The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine

121719495@qq.com15620196831

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026