Puerarin for the prevention and treatment of chronic postoperative pain: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR2025001544

Enrollment

Unknown

Registered

2025-08-09

Start date

2023-06-25

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

Control:saline solution of the same volume

Puerarin:Puerarin injection 400mg/day*7 days

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Single-port VATS lobectomy or sublobectomy; (2) Age= 18 years old; (3) Informed consent voluntarily participate in the trial and sign the informed consent form

Exclusion criteria

Exclusion criteria: (1) History of chronic pain in the past; (2) secondary surgery; (3) Long-term use of psychotropic and analgesic drugs; (4) Subjects who are considered by the investigator to be inappropriate to participate in this study.

Design outcomes

Primary

Measure	Time frame
Incidence of chronic pain 3 months after surgery;	—

Secondary

Measure	Time frame
Acute pain NRS score at 24h/48h and/72hhours after surgery;Analgesia within 3 months after surgery;incidence of adverse reactions;Pittsburgh Sleep Index (PSQI);Chronic pain NRS score 3 months after surgery;Hamilton Anxiety/Depression (HAMA/HAMD);Consumption and frequency of rescue analgesics;SF-36 quality of life;	—

Countries

china

Contacts

Public ContactLu Peichun

Kunshan Traditional Chinese Medicine Hospital

kzylpc@126.com18549800680

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026