Male infertility combined with obesity
Conditions
Interventions
Treatment group:lingji formula
Sponsors
Xiyuan Hospital Chinese Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Age
22 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Meanwhile meet the western medical diagnostic criteria of male infertility and oligoasthenozoospermia and obesity; (2) Meet the traditional Chinese medicine diagnostic criteria of kidney essence deficiency and dampness in the essence chamber; (3) 22 years old = age = 45 years old; (4) Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Congenital chromosomal abnormalities or microdeletions of the Y chromosome or other known hereditary diseases that may cause sterility; or obstructive azoospermia resulting in infertility; (2) Combined with moderate to severe varicocele cryptorchidism or orchitis or epididymitis or mycoplasma or chlamydia or other diseases that clearly affect semen quality; (3) Combined with erectile dysfunction of ejaculation abnormality or other sexual dysfunctions resulting in the inability to complete intravaginal ejaculation; (4) Combined with diabetes mellitus requiring long-term medication to control blood glucose; (5) Combined with hepatic insufficiency or renal dysfunction (hepatic insufficiency defined as alanine aminotransferase and/or aspartate aminotransferase is more than 1.5 times of the upper limit of normal value and renal dysfunction defined as blood urea nitrogen and/or creatinine is more than the upper limit of normal value) or serious cardiovascular diseases or serious cerebrovascular diseases or hematopoietic system diseases or psychiatric diseases or other complications; (6) History of allergy to any drugs or ingredients used in this study; (7) Receipt of other relevant treatments for this disease such as aromatase inhibitors or estrogen antagonists etc. two weeks prior to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total progressive motile sperm count; | — |
Secondary
| Measure | Time frame |
|---|---|
| waist-to-hip ratio;Traditional Chinese medicine symptom score;sperm concentration;total cholesterol;percentage of progressive motility spermatozoa;triglyceride;pregnancy rate;percentage of normal morphology spermatozoa;body mass index;percentage of progressive motility spermatozoa plus percentage of non-progressive motility spermatozoa;semen volume;low-density lipoprotein; | — |
Countries
China
Contacts
Public ContactGuo Jun
Xiyuan Hospital Chinese Academy of Chinese Medical Sciences
Outcome results
None listed