intercritical gout
Conditions
Interventions
treatment group:taking Biqi capsules (4 capsules at a time, 2 times a day
Control group:do not take Biqi capsules
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.The study subjects met the 2015 ACR/EULAR diagnostic criteria for gouty arthritis and the stage of disease met the 2023 Guidelines for the Diagnosis and Treatment of Gout and Hyperuricemia with Integrated Traditional Chinese and Western Medicine for for intercritical gout and were receiving a stable dose of urate-lowering drugs (allopurinol/febuxostat/benzbromarone) for non-acute gout. 2.The TCM syndrome type belongs to the damp turbidity internal accumulation pattern or the cold and dampness obstruction pattern or the phlegm stasis obstruction pattern. 3.Age between 18-80 years old gender is not limited. 4.Voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: Potential subjects who meet the inclusion criteria will be excluded if they meet any of the following: 1.Patients with severe cardiovascular brain lung liver kidney hematopoietic system diseases malignant tumors and psychiatric diseases. 2.Women who are pregnant or breastfeeding. 3.Patients with active gastroduodenal ulcer or gastritis due to long-term use of non-steroidal anti-inflammatory drugs. 4.Patients with secondary gout caused by the presence of underlying medical conditions or drug use. 5.Those who are known to be allergic to Biqi capsules or any of their components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of episodes of pain caused by MSU crystal dissolution; | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte sedimentation rate;the position and quantity of the involved joint;THE HEALTH ASSESSMENT QUESTIONNAIRE (HAQ) DISABILITY INDEX (DI) OF THE CLINICAL HEALTH ASSESSMENT QUESTIONNAIRE;recurrence frequency;serum urate (SU) level;VAS score during gout flares;interval time of gout flares;Color Doppler Flow Imaging of joints;gout flare duration;C-reactive protein; | — |
Countries
China
Contacts
Public ContactChenXiumin
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed