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A randomized controlled study on the efficacy of acupuncture with a pestle needle combined with antidepressant in the acute phase of depression

A randomized controlled study on the efficacy of acupuncture with a pestle needle combined with antidepressant in the acute phase of depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001494
Enrollment
Unknown
Registered
2025-07-26
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drepression

Interventions

control group:SSRI(Selective Serotonin Reuptake Inhibitor)
Intervention group:pestle neddle and SSRI(Selective Serotonin Reuptake Inhibitor)

Sponsors

Sichuan Clinical Medical Research Center for Mental Disorders Chengdu China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1 conforms to DSM-5 (Diagnostic and Statistical Manual of Mental Disorders DSM-5) Diagnostic criteria for depression (i.e. the acute attack period); 2. HAMD score =8; 3. Age: 18-65 years old; 4. Ethnicity: Han; 5. Clear consciousness and able to cooperate with treatment; 6. Understand the content of the informed consent form and sign it.

Exclusion criteria

Exclusion criteria: 1. Patients with organic brain diseases neurological disorders and severe endocrine or metabolic disorders; 2. Those with other DSM-5 axis I and II disorders (such as schizophrenia material-related disorders and delayed mental development) "Delay etc." 3. Those who do not cooperate with the treatment or cannot effectively complete the treatment; 4. Those with suicidal tendencies; 5. Pregnant and lactating women; 6. Do not use pestle on areas with skin infections boils ulcers scars or tumors. 7. Patients who are currently participating in other intervention studies.

Design outcomes

Primary

MeasureTime frame
HAMD-24 scale (Hamilton Depression Rating Scale - 24 items version);

Secondary

MeasureTime frame
PSQI scale (Pittsburgh Sleep Quality Index) ;HAMA Scale (Hamilton Anxiety Scale);

Countries

China

Contacts

Public ContactZhe Li

Sichuan Clinical Medical Research Center for Mental Disorders Chengdu China

jay_li@163.com18980606722

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026