Cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) The diagnosis meets the diagnostic criteria revised by the Fourth National Stroke Conference and is confirmed by head CT or MRI examination; 2) Within 6 months after stroke there are abnormalities in the Mini Mental State Examination (MMSE) (abnormal reference values and explanations: illiteracy = 19; primary school = 24; junior high school and above = 27); Montreal Cognitive Assessment Scale (MoCA) abnormality (abnormal reference values and explanations: illiteracy = 13; primary school = 19; junior high school and above = 24); 3) Good audio-visual and normal olfactory function; 4) Capable of normal language communication;
Exclusion criteria
Exclusion criteria: 1) The subject already had cognitive impairment before the onset of the disease; 2) The subjects experienced adverse reactions such as allergies dizziness etc. during the intervention process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| homocysteine (Hcy);brain-derived neurotrophic factor(BDNF); | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination;Montreal Cognitive Assessment; | — |
Countries
China
Contacts
Hebei Medical University Dental Hospital