Post-stroke cognitive impairment
Conditions
Interventions
Conventional acupuncture group:Acupuncture treatment administered 30 days post-stroke
Control group: Conventional Western medical treatment no acupuncture
Ultra-early intervention group:Acupuncture treatment administered 7 days post-stroke
Early intervention group:Acupuncture treatment administered 14 days post-stroke
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with ischemic stroke onset within 6 months; (2) Aged 30-75 years with an education level of at least elementary school; (3) Capable of daily living activities with a Barthel index of =60; (4) No cognitive function abnormalities at enrollment with a Montreal Cognitive Assessment (MoCA) score of =18; (5) Mini-Mental State Examination (MMSE): MMSE score >17 (illiterate) or MMSE score >20 (elementary school level) or MMSE score >24 (middle school level or higher); (6) The patient must sign an informed consent form and cooperate with the treatment.
Exclusion criteria
Exclusion criteria: (1) Patients diagnosed with cognitive impairment before cerebral infarction; (2) Patients currently taking medications that may interfere with the evaluation of the efficacy of the study treatment including cholinesterase inhibitors cytosine or those who have received traditional Chinese medicine or acupuncture treatment before enrollment; (3) Patients who are unable to complete the assessment due to severe mental cognitive or emotional disorders during the screening process; (4) Patients with severe diseases of the heart liver kidneys or other organs; (5) Pregnant women planning to become pregnant or breastfeeding women; (6) Patients recruited to participate in other clinical trials related to acupuncture or cognitive impairment within the last month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA);"Incidence of PSCI";Mini-mental State Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activities of daily living ADL;quality of life score QOL;Changes in MRI brain networks;Hamilton Depression Rating Scale;Brunnstrom Movement Therapy;Fugl Meyer Assessment;Issues Diagnosis Scale for Ischemic Stroke Symptoms;Hamilton Anxiety Rating Scale; | — |
Countries
China
Contacts
Public ContactRuiwen Fan
Peking University Third Hospital
Outcome results
None listed