Parkinson's disease
Conditions
Interventions
Control Group:Auricular Non-Vagus Nerve Stimulation Group
Experimental Group:Transcutaneous Auricular Vagus Nerve Stimulation Group
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosis of Parkinson's disease (PD) meets the "2015 MDS Diagnostic Criteria for Parkinson's Disease" without head tremor. 2.Hoehn and Yahr stage is between I and III. 3. Age between 35 and 80 years. 4.The patient voluntarily agrees to participate in this study and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients diagnosed with secondary parkinsonism or Parkinson-plus syndromes. 2.Patients with severe diseases of the heart liver kidneys or hematopoietic system or with malignant tumors; those with other neurological disorders psychiatric conditions a history of traumatic brain injury or previous brain surgery. 3.Patients who are unable to undergo fMRI examination for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Movement Disothe Unified Parkinsons Disease Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Assessment of Constipation – Symptoms;fMRI;Patient Assessment of Constipation – Quality of Life;Hamilton Depression Rating Scale;Scales for Outcomes in Parkinson's Disease – Autonomic;Hamilton Anxiety Rating Scale; | — |
Countries
China
Contacts
Public ContactZhe Li
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine)
Outcome results
None listed