depressive disorder
Conditions
Interventions
Yueju pill group:Yueju Pill Treatment
Escitalopram group:Escitalopram treatment
Sponsors
Jinan University First Affiliated Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Meet DSM-5 diagnostic criteria for depressive disorder; 2.12-17 years old; 3.HAMD-24>20 YMRS<6; 4. Never used traditional Chinese medicine or western medicine with antidepressant effect in the past week; 5. The subject gives informed consent and the person and/or the legal guardian sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. People with a history of drug allergy; 2. People who cannot understand the content of the scale due to consciousness language disorders or insufficient intelligence or cultural level; 3. People who have combined severe physical and organic brain diseases; 4. People who are comorbid schizophrenia spectrum and other psychotic disorders; 5. People who have received two full courses of antidepressant treatment but have not yet been relieved; 6. People who are at a serious risk of suicide; 7. People who are unable to follow the research plan; 8. People who are alcoholic and/or psychoactive substances substance abusers and those who depend on (including sleeping pills).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-item Hamilton Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Constitution in Chinese Medicine Questionnaire;Children's Depression Inventory; | — |
Countries
China
Contacts
Public ContactYanbin Jia
Jinan University First Affiliated Hospital
Outcome results
None listed