Vascular dementia
Conditions
Interventions
Vascular dementia is a syndrome (spleen and kidney deficiency phlegm and blood stasis interconnection group):Observation
Vascular dementia non-evidence group (non-spleen and kidney deficiency non-phlegm and blood stasis interaction group): Observation
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for vascular dementia; (2) Hachinski Ischemic Scale score =7; (3) Aged between 45 and 80 years old regardless of gender; (4) Clinical Dementia Rating (CDR) scale assessed as mild or moderate dementia (CDR=1.0 or 2.0); (5) Capable of cooperating to complete the trial tests; (6) The volunteer participant and their legal guardian have signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with clearly diagnosed dementia caused by brain diseases other than VaD or those suspected of such conditions based on existing medical history scales or imaging examinations including Alzheimer's disease Lewy body dementia frontotemporal dementia Parkinson's disease central nervous system demyelinating diseases tumors hydrocephalus trauma central nervous system infections etc.; (2) Patients with severe neurological deficits who are unable to complete examinations such as hemiplegia of the dominant hand various types of aphasia or visual/auditory impairments; (3) Individuals with severe mental disorders (e.g. depression schizophrenia) or epilepsy; (4) Those with alcohol or substance abuse issues.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VaDAS-cog;ADL;MMSE;Peripheral symptoms record form;CDR;Core Symptoms Observation Form;Hachinski; | — |
Secondary
| Measure | Time frame |
|---|---|
| SRSS;GAD-7;SARC-Calf;FRAIL;GDS-5;Morse;Pulse diagnosis information collection;Observation information collection;MNA;Four Needles Information Record in Traditional Chinese Medicine; | — |
Countries
China
Contacts
Public ContactZhang Yunling
Xiyuan Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed