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A clinical study on the intervention of acupuncture in adolescents with subthreshold depression and the brain mechanism of TMS-EEG

A clinical study on the intervention of acupuncture in adolescents with subthreshold depression and the brain mechanism of TMS-EEG

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001429
Enrollment
Unknown
Registered
2025-07-16
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adolescents with subthreshold depression

Interventions

sham acupuncture:sham acupuncture
observation group:acupuncture

Sponsors

Medical Ethics Committee of Shenzhen Bao'an Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 18 Years

Inclusion criteria

Inclusion criteria: (1) Adolescents between the ages of 12~18; (2) Adolescent Self-Rating Life Events Scale (ASLES) showed moderate or severe chronic stress levels; (3) A score of 5 = Patient Health Questionnaire-9 (PHQ-9) < 10 points and did not meet the diagnostic criteria for DSM-V moderate-major depressive disorder.

Exclusion criteria

Exclusion criteria: (1) are taking antidepressants; (2) history of alcohol dependence; (3) have a clear history of psychiatric illness; (4) there is a risk of suicide; (5) significant cognitive impairment; (6) Recent bereavement.

Design outcomes

Primary

MeasureTime frame
Adolescent Depressive Symptom Rating Scale;—

Secondary

MeasureTime frame
Patient Health Questionnaire-Somatic Symptom Group Scale;EEG resting state;EEG emotion-evoking task;—

Countries

China

Contacts

Public ContactZhou Peng

Shenzhen Bao'an Hospital of Traditional Chinese Medicine

zhoupeng80@gzucm.edu.cn13714077462

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026