pulmonary pure ground-glass nodules
Conditions
Interventions
Control Group:placebo
Intervention Group:Chuanjie granules
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) An imaging report from the past three months identifies a pGGN as the largest pulmonary nodule deemed appropriate for active surveillance rather than surgical intervention following a multidisciplinary consultation; (2) Aged 18-75 years irrespective of sex; (3) Voluntarily providing written informed consent.
Exclusion criteria
Exclusion criteria: (1) Existing cancer or major organ disease; (2) Current respiratory infection; (3) The use of antibiotics hormonal therapies immunosuppressants or Chinese herbal medications within the preceding three months; (4) Psychiatric or cognitive issues hindering study compliance; (5) The state of pregnancy or lactation; (6) A known hypersensitivity to any component of the study product; (7) Concurrent participation in another clinical trial within the preceding month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in the maximum diameter of the pGGN from baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nodule density;Sf-36 (Short Form-36) score;Malignant risk of pulmonary nodules;Reduction rate of the maximum nodule diameter;Oral (saliva), intestinal (feces) flora characteristics;Anxiety and depression score; | — |
Countries
China
Contacts
Public ContactYou Fengming
Hospital of Chengdu University of Traditional Chinese Medicine 39 Shi-er-qiao Road Chengdu Sichuan China.
Outcome results
None listed