Acute pharyngitis in children
Conditions
Interventions
Control group:10% Lanqin oral liquid oral. 3= age = 6 years old 0.5 vials (5ml) at a time one day 3 times
6< age= 12 years old 1 bottle (10ml) at a time 3 times a day
Experimental group:Lanqin oral liquid oral. 3= age = 6 years old 0.5 sticks (5ml) at a time 3 times a day
Sponsors
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for acute pharyngitis. (2) Meets the traditional Chinese medicine differentiation criteria for lung stomach heat syndrome. (3) Age range from 3 to 12 years old (<13 years old). (4) Randomly enrolled with a disease duration of = 48 hours and a Wong Baker facial expression pain score (WBS) of = 4 for the most severe sore throat within the day prior to screening. (5) The informed consent process should comply with regulations and the legal guardian or participant (= 8 years old) should jointly sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Acute pharyngitis caused by non infectious factors such as dust smoke and irritant gases acute suppurative tonsillitis (acute follicular tonsillitis and acute crypt tonsillitis) grade III tonsillar enlargement peritonsillar abscess or posterior pharyngeal wall abscess and pharyngeal symptoms caused by other diseases. (2) Individuals who test positive for rapid streptococcal antigen. (3) The white blood cell count absolute neutrophil count and CRP all exceeded the upper limit of normal (ULN) by 1.2 times and the researchers considered it to be a bacterial infection or the need for antibiotic treatment. (4) The prodromal or accompanying symptoms of acute infectious diseases such as measles scarlet fever infectious mononucleosis etc. (5) Children with complications such as acute pharyngitis otitis media bronchitis pneumonia etc. (6) Abnormal liver and kidney function [AST ALT Scr>upper limit of normal] evaluated by researchers as clinically significant. (7) Individuals with severe primary diseases of the heart lungs liver kidneys metabolism hematopoiesis immune nervous and psychiatric systems. (8) Children or their parents/caregivers who have difficulty understanding or cannot cooperate with the use of WBS scoring. (9) Those who have used traditional Chinese and Western medicine drugs to treat this disease 48 hours before diagnosis and have been judged by researchers to have an impact on the evaluation of therapeutic efficacy. (10) Individuals who are allergic to the experimental medication and its components. (11) Individuals who have participated in or are currently participating in other clinical trials and have received investigational drug treatment within the past 3 months prior to the trial. (12) Researchers believe that participants should not be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sore throat disappearance rate after 5 days of medication; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM Pattern Score/Efficacy (Effective);Sore throat WBS score;Efficacy of pharyngeal signs (rate of normalization);Time for the sore throat to disappear;Onset of action for sore throat;Disease efficacy (recovery rate);Use of emergency medications;Efficacy of individual symptoms (disappearance rate); | — |
Countries
China
Contacts
Public ContactPing Rong
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed