psoriasis
Conditions
Interventions
1:External use of 10% urea ointment with oral Chinese herbal decoction
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age range: 18 - 70 years old gender not restricted; (2) Meets the diagnostic criteria for psoriasis vulgaris; (3) The severity of skin lesions is moderate (PASI < 10); (4) Has signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Reverse type joint type pustular type erythrodermic type psoriasis. (2) Pregnant or lactating women or those planning to get pregnant within one year. (3) Patients with severe primary diseases in the respiratory system circulatory system digestive system endocrine system and urinary system that cannot be controlled by conventional medication; patients with severe infections hepatitis tuberculosis lymphocyte proliferation hematological system abnormalities tumors; patients with severe water electrolyte and acid-base balance disorders; patients with primary or secondary immune deficiencies and hypersensitivity; or patients whose clinical test indicators fall into one of the following situations: alanine aminotransferase or aspartate aminotransferase is more than 1.5 times the upper limit of the normal value; creatinine is more than 1.5 times the upper limit of the normal value; hemoglobin is more than 20g/L above the upper limit of the normal value; platelet count is less than 75×10*9/L; white blood cell count is less than 3.0×10*9/L; blood potassium is higher than 5.5mmol/L or lower than 3mmol/L; or other laboratory test abnormalities. Researchers determine that they are not suitable to participate in this trial. (4) Patients who are known to be allergic to the drugs used in this study or allergic to the components of related drugs. (5) Patients who are currently participating in other drug clinical trials or have participated in other clinical trials within one month. (6) Patients considered not suitable for inclusion by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement rate of Psoriasis Area and Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skindex-16 Quality of Life Measure;Static Physician's Global Assessment score for psoriasis severity;Visual Analog Scale (VAS) score;Body Surface Area;Dermatology Life Quality Index (DLQI) score; | — |
Countries
China
Contacts
Public ContactXu Haowei;Yan Yuhong
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed