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Acupuncture has a significant effect on the ocular surface nerve and ocular surface pain in dry eye patients Clinical study on the influence of tear inflammatory factors

Acupuncture has a significant effect on the ocular surface nerve and ocular surface pain in dry eye patients Clinical study on the influence of tear inflammatory factors

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001399
Enrollment
Unknown
Registered
2025-07-13
Start date
2025-04-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

Acupuncture Group:Acupuncture
Sham acupuncture group:Sham acupuncture

Sponsors

Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) meet the diagnostic criteria of dry eye; At the same time it was accompanied by ocular pain > dryness burning sensation foreign body sensation and one of the symptoms of ocular surface neuralgia. (2) age >18 years old <40 years old (3) Anesthetic treatment was effective (4) no other active inflammation except dry eye no serious cardiovascular cerebrovascular and systemic diseases; (5) no other treatment or medication was taken during the treatment period; (6) Informed consent was signed

Exclusion criteria

Exclusion criteria: (1) patients with eye pain caused by other diseases such as glaucoma herpes zoster (2) dry eye treatment using methods other than those used in this study (3) abnormal corneal sensation (4) history of ocular surgery or trauma within 6 months (5) contact lens wearing history within 1 month (6) complicated with other underlying diseases requiring long-term medication or serious systemic diseases (7) pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
IL-17Ainflammatory factor in tears;Corneal nerve length;IL-8 inflammatory factor in tears;The number of corneal immune cells;IL-9 inflammatory factor in tears;Corneal nerve branch density;MM-9 in the tear;Corneal nerve tortuosity;Corneal nerve density;

Secondary

MeasureTime frame
BUT;NPSI-EYE;OSDI;ST;FL;DEQS;

Countries

China

Contacts

Public ContactYing Yu

Staff and workers

loyis81@163.com13941644011

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026