obesity with impaired glucose regulation
Conditions
Interventions
Control group:Konjac flour meal replacement
Experimental Group:Sanren Douling Meal Replacement
Sponsors
xiyuan hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) 18 years = Age = 65 years gender not limited; (2) Meets the diagnostic criteria for obesity and impaired glucose regulation; (3) Meets the criteria for phlegm-dampness constitution according to the "Classification and Determination of Constitution in Traditional Chinese Medicine"; (4) The subject voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Combined with hepatic and renal insufficiency (liver function ALT and/or AST greater than 1.5 times the upper limit of normal renal function CR greater than the upper limit of normal) severe cardiovascular and cerebrovascular diseases hematopoietic system diseases mental illness and other comorbidities. (2) Women with fertility requirements in the past six months pregnant women or breastfeeding women. (3) Those with mental abnormalities or poor compliance. (4) Individuals with allergic constitution or known allergy to the study drugs. (5) Those taking Western medications such as metformin and acarbose as well as Chinese patent medicines with hypoglycemic effects. (6) Patients who have received treatment with Chinese or Western weight-loss drugs or participated in other drug clinical trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in BMI after 8 weeks of treatment;Changes in fasting blood glucose levels after 8 weeks of treatment;Changes in blood glucose levels 2 hours after meals for 8 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| body fat percentage;Insulin resistance related indicators ( adiponectin fasting insulin insulin resistance index );Waist circumference and waist-to-hip ratio;Phlegm dampness constitution conversion points;Lipid-related levels ( total cholesterol triglyceride low-density lipoprotein cholesterol high-density lipoprotein cholesterol );fatigue self-assessment scale;Proportion of changes in impaired glucose regulation; | — |
Countries
China
Contacts
Public ContactWang Peili
xiyuan hospital China Academy of Chinese Medical Sciences
Outcome results
None listed