Postherpetic neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients meets the diagnostic criteria of PHN and the affected area is located in the thoracic and costal regions or the waist and abdomen. (2) Age 50-75 years old male or female and the disease course is = 12 months; ?(3) 4 points = Visual Analogue Scale (VAS) score = 8 points; ?(4) No medication or other treatment methods have been taken for PHN in the past two weeks;Not participating in other ongoing clinical studies; (5) The patient agreed to participate in this study signed the informed consent form and was able to cooperate in completing various evaluations and interventions.
Exclusion criteria
Exclusion criteria: (1) Some special types of herpes zoster patients, such as PHN patients caused by perineum, generalized herpes zoster, etc; (2) Patients who take relevant analgesic drugs before enrollment, are unwilling to undergo elution, or have serious safety issues during elution or observation period. Patients who have undergone nerve intervention surgery or other neurosurgical treatments for PHN; (3) Those with damaged skin in the painful area; Individuals with a history of allergy to amide local anesthetics and those who are allergic to the investigational drug; (4) Individuals who have used glucocorticoids or immunosuppressants within one month; Pathological neuralgia due to other reasons (such as diabetes, trigeminal neuralgia, etc.) and cancer pain patients; (5) Patients currently taking Class I antiarrhythmic drugs (i.e. lidocaine, metoprolol, phenytoin sodium, etc.); (6) Patients with combined systemic infections, severe heart, liver, kidney, blood and other systemic diseases, or malignant tumors; Or combined with coagulation dysfunction; (7) Patients with mental illnesses, such as severe anxiety and depression; Individuals with a history of opioid or tranquilizer drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology life quality index;Self-rating anxiety scale;Pittsburgh sleep quality index;Self-rating depression scale; | — |
Countries
China
Contacts
The Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine