Lumbar Spinal Stenosis
Conditions
Interventions
Control Group:Routine postoperative treatment for lumbar spine surgery +Kai Xin San placebo
Treatment Group:Routine postoperative treatment for lumbar spine surgery +Kai Xin San
Sponsors
Sichuan Province Orthopedic Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) patients aged 60 - 80; 2) with typical intermittent claudication; 3) physical examination: positive lumbar extension test; 4) CT and MRI scans indicative of lumbar spinal canal stenosis at L4/5, L3/4, or L5/S1; 5) candidates for posterior TLIF surgery.
Exclusion criteria
Exclusion criteria: 1) Patients with lumbar instability, spondylolisthesis, tumors, or infection; 2) Patients presenting with cauda equina syndrome, such as abnormal bowel/bladder function or saddle anesthesia; 3) Patients with a history of trauma leading to low back and lower limb pain/numbness; 4) Patients with severe cardiopulmonary diseases or hepatic/renal dysfunction, who cannot tolerate surgery or anesthesia; 5) Patients diagnosed with anxiety or depressive disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale;5-hydroxytryptamine;Oswestry disability index;Brain-Derived Neurotrophic Factor;Hospital Anxiety and Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;CRP;Heart rate;surgical duration;Length of hospital stay,;IL-1ß;blood loss;ESR; | — |
Countries
China
Contacts
Public ContactWang Ye-Hui
Sichuan Province Orthopedic Hospital
Outcome results
None listed