diabetic kidney disease
Conditions
Interventions
Control Group :Placebo acupoint application at the Shenshu acupoints
Treatment Group??:"Yishen Huoxue Formula" acupoint application at the Shenshu acupoints
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age: 18 - 80 years old no gender limitation. (2) Meet the above diagnostic criteria for T2DM. (3) Meet the high-risk population identification criteria for DKD occurrence with a score =80 where the score is calculated as: 1+exp(-3.306+0.698×Gastrointestinal Real-Heat Syndrome+0.781×Spleen - Kidney Yang Deficiency Syndrome+1.024×UA+0.911×Duration of Disease+0.042×Age) exp(-3.306+0.698×Gastrointestinal Real-Heat Syndrome+0.781×Spleen - Kidney Yang Deficiency Syndrome+1.024×UA+0.911×Duration of Disease+0.042×Age) ?(4) Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1) Exclude patients with Type 1 diabetes and other non-Type 2 diabetes mellitus (non-T2DM) conditions; 2) Clinical diagnosis suggests diabetic kidney disease (DKD) or the presence of other kidney diseases; 3) Have not received acupoint plaster therapy or taken other traditional Chinese medicine or proprietary Chinese medicine with similar components and therapeutic effects to "Yishen Huoxue Prescription" within the past 12 months; 4) Have experienced severe infections severe anemia electrolyte disturbances or other complications within the past 4 weeks; 5) Accompanying acute kidney injury oliguria or anuria severe edema large pleural effusions or ascites; 6) Have had severe heart brain liver and hematopoietic system diseases within the past three months: stroke transient ischemic attack significant neurological dysfunction remaining after stroke myocardial infarction unstable angina ischemic heart disease with coronary artery bypass or PCI surgery congestive heart failure (NYHA class III-IV) transaminase leve
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diabetic Kidney Disease (DKD) Incidence;Renal function level;Albuminuria level; | — |
Secondary
| Measure | Time frame |
|---|---|
| ELISA detection of kidney - damage - related biomarkers nephrin;blood rheology testing;ELISA detection of kidney - damage - related biomarkers podocin;multimodal biometric monitoring;ELISA detection of kidney - damage - related biomarkers: klotho; | — |
Countries
China
Contacts
Public ContactLiu Hongfang
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Outcome results
None listed