Chronic Renal Failure
Conditions
Interventions
Traditional Chinese Medicine (TCM) Compound Formula Group for Qi Deficiency with Blood Stasis Pattern:Yiqi Xiaozheng Formula+Standard Treatment
Control Group with Yang Deficiency and Blood Stasis Pattern:Standard Treatment
Healthy Control Group:Non-Intervention Control
Control Group with Qi Deficiency and Blood Stasis Pattern:Standard Treatment
Traditional Chinese Medicine (TCM) Compound Formula Group for Yin Deficiency with Blood Stasis Pattern:Buxu Xiaozheng Formula+Standard Treatment
Control Group with Yin Deficiency and Blood Stasis Pattern:Standard Treatment
Traditional Chinese Medicine (TCM) Compound Formula Group for Yang Deficiency with Blood Stasis Pattern:Wenyang Xiaozheng Formula+Standard Treatment
Sponsors
Ningbo Municipal Hospital of Traditional Chinese Medicine(TCM) Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Chronic Kidney Disease (CKD) Patients:1)Meeting the Western diagnostic criteria for chronic kidney disease (CKD stages 3-5);2)TCM syndrome differentiation consistent with:Qi deficiency with blood stasis or Yang deficiency with blood stasis or Yin deficiency with blood stasis;3)Age between 18–75 years;4)Controlled comorbidities including infections acidosis electrolyte imbalances and hypertension;5)Willingness to participate with signed informed consent for clinical research. Inclusion Criteria for Healthy Controls1)Healthy volunteers (non-therapeutic participation) without diseases relevant to the study;2)Healthy volunteers (non-therapeutic participation) without diseases relevant to the study;3)Availability of complete medical records and signed informed consent.
Exclusion criteria
Exclusion criteria: 1)Pregnancy or lactation;2)Severe comorbidities including:major primary diseases of the heart brain liver or hematopoietic systemsevere infectionsmalignancy (cancer)allergy/hypersensitivity to the investigational drugs;3)Non-cooperative patients such as those with psychiatric disorders affecting compliance;4)Refusal to participate including:unwillingness to undergo treatmentdeclining to sign the informed consent form. Any of the above conditions will lead to exclusion from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Serum Calcium;Serum Albumin;Urine Protein-to-Creatinine Ratio;Serum Phosphorus;Traditional Chinese Medicine (TCM) Symptom Score;Parathyroid Hormone;Serum Beta Microglobulin;Lipid Profile; | — |
Countries
CHINA
Contacts
Public ContactCai Xudong
Ningbo Municipal Hospital of Traditional Chinese Medicine(TCM) Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed