Ulcerative colitis
Conditions
Interventions
Treatment group:Jianpi Huashi Bushen granule
Control group:Mesalazine + Jianpi Hua dampness bushen granule simulator
Sponsors
Shuguang Hospital affiliated to Shanghai University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-75 years old; 2) The clinical diagnosis was ulcerative colitis; 3) TCM syndrome is in line with spleen-kidney Yang deficiency type; Sign informed consent have good compliance with the observation and treatment of researchers and voluntarily participate.
Exclusion criteria
Exclusion criteria: 1)Intestinal inflammatory diseases caused by other causes: bacterial dysentery amoebic dysentery chronic schistosomiasis intestinal tuberculosis and other infectious colitis and Crohn's disease ischemic enteritis radiation enteritis high-grade intraepithelial neoplasia of the rectum stool virus or bacteria test positive patients; 2)Combined with serious underlying diseases such as cardiovascular and cerebrovascular liver kidney lung and other serious primary diseases and other serious complications; 3)Severe gastrointestinal diseases: toxic megacolon gastrointestinal tumor gastrointestinal perforation gastrointestinal hemorrhage intestinal obstruction etc.; 4)Have serious mental disorders communication barriers unable to cooperate with diagnosis and treatment; 5)Pregnant and lactating women or women of gestational age who are preparing for pregnancy and patients who are allergic to therapeutic drugs; 6)Patients who have taken drugs that should not be shared with mesalazine such as thiguanine mercaptopurine ampicillin prosulfa warfarin methotrexate folic acid etc. in the past 1 week or who have received varicella vaccine or steroid drugs such as prednisone; 7)Patients who participated in other clinical trials within the past 1 month; 8)Patients who have used biologics within the past 1 month; 9)Severe allergy and allergy to mesalazine or known components of Chinese medicine granules.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mayo score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baron score;TCM syndrome score;ulcerative colitis endoscopic index of severity;Ulcerative Colitis-Symptom Questionnaire;truelove and witts classification;Geboes score;Inflammatory Bowel Disease Questionnaire; | — |
Countries
China
Contacts
Public ContactWei-Wei Hao
Shuguang Hospital affiliated to Shanghai University of TCM
Outcome results
None listed