Hypertension
Conditions
Interventions
Control Group:oral amlodipine besylate tablet group:Oral administration of amlodipine besylate tablets 5 mg each time once a day for 3 consecutive months.
Intervention Group:Oral Pingmai Zhixuan Pill Group:Take Pingmai Zhixuan Pills orally, 6g each time, twice a day, for a course of 3 months
Sponsors
Kaifeng Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age 60-80 years old; 2) Western medicine diagnostic criteria: meet the latest "Hypertension Guidelines" in May 2020 Grade 1 (mild) hypertension criteria that is 2-3 consecutive blood pressure measurements within 1-4 weeks with systolic blood pressure of 140-159 mmHg and/or diastolic blood pressure of 90-99 mmHg in the clinic; 3) Chinese medicine diagnostic criteria: meet the diagnostic criteria of liver yang hyperactivity syndrome in Chinese medicine and refer to the "Guidelines for Clinical Research of New Chinese Medicines (Trial)" for diagnosis. Main symptoms: dizziness headache irritability; Secondary symptoms: flushed face red eyes dry mouth bitter mouth constipation red urine red tongue with yellow fur and stringy pulse. 4) Voluntary participation in this study and signing of informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with secondary hypertension; 2) Patients with heart liver kidney brain and other diseases (amlodipine besylate tablets should be used with caution in patients with angina pectoris myocardial infarction heart failure liver dysfunction and renal failure); 3) Patients with intellectual disabilities or mental and behavioral abnormalities who cannot cooperate with treatment and observation; 4) Patients who are allergic to the components of the drug in this study and have drug contraindications; 5) Patients with spleen and stomach deficiency and cold and yin deficiency constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM symptom score;24-hour Blood Pressure;Duchenne hypertension quality of life score;Total effective rate of drug efficacy; | — |
Countries
China
Contacts
Public ContactTao Zhu
Kaifeng Traditional Chinese Medicine Hospital
Outcome results
None listed