Acute gastrointestinal injury in sepsis
Conditions
Interventions
Control group:The primary disease and active anti-infection treatment and leave a gastric tube, after the basic stabilization of circulatory and respiratory functions, the implementation of enteral nu
Observation group:On the basis of treatment in the control group, Xuanfei Tongfu Yin was added: 100mL of concentrated decoction was taken, 2 doses per day, 1 dose for nasal feeding and 1 dose for enem
Sponsors
the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital ofTraditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
65 Years to 110 Years
Inclusion criteria
Inclusion criteria: 1) Age =65 years; 2) Meet the diagnostic criteria of sepsis and acute gastrointestinal injury; 3) Patients or family members were conscious knew the content of the study and voluntarily and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1)Age <65 years old 2) Those who have one of the following conditions: severe cardiac insufficiency serious primary diseases such as liver kidney hematopoietic system; 3) Those with the previous existence of serious gastrointestinal diseases such as peptic ulcer inflammatory bowel disease digestive tract tumors; 4) Hemodynamic still not stabilized after 24 hours of ICU admission; 5) Family members refused participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DAO;Bedside Colonic ultrasound examination;D-Lac;SOFA points;APACHE? points;TNF-a;IL-6;IL-10;Heparin binding protein;Bedside Gastric antrum ultrasound examination;I-FABP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilation duration;28 day mortality rate;PCT;Duration of vasoactive drug use in patients with combined shock;CRP;EICU hospital acquired pneumonia;Abdominal pressure measurement;ICU stay time;AGI grading;Damage to liver and kidney function;Status of acquired pneumonia in EICU hospital; | — |
Countries
China
Contacts
Public ContactQingyu Jiang
the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital ofTraditional Chinese Medicine)
Outcome results
None listed