Patients with type 2 diabetes mellitus complicated with small cerebral vessel disease
Conditions
Interventions
Taijiquan group:On the basis of the health education group, the Taijiquan group received 24 simplified Taijiquan training for 60 minutes three times a week for 24 consecutive weeks. No one participate
Health Education Group:Provide health education on the causes and prevention of type 2 diabetes and small vessel disease. Do not participate in other special physical exercises during the intervention
Sponsors
The Second People's Affiliated Hospital of Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age 40-70 years old regardless of gender; 2) It meets the diagnostic criteria of T2DM and CSVD and at least one imaging marker of CSVD can be seen on skull MRI; 3) There is no serious audio-visual or cognitive impairment and can cooperate with the completion of various examinations; 4) Sound limbs and no contraindications for exercise; 5) Agree to join the study and sign the informed consent form. Only those who meet the above conditions can be enrolled.
Exclusion criteria
Exclusion criteria: 1)Cognitive dysfunction; 2)Patients with previous cerebral infarction cerebral hemorrhage and other related organic brain diseases or infectious diseases of nervous system and neurological function defects caused by intracranial macrovascular diseases; 3)Patients with acute complications of diabetes such as diabetic ketoacidosis and hyperosmolar coma; 4)Patients with serious primary diseases or malignant tumors such as heart liver and kidney; 5)patients with serious mental diseases or mental disorders; 6)Suffering from nerve muscle joint and other diseases affecting motor function; 7)Pregnant or lactating women; 8)The cumulative time of regular exercise per week exceeded 1.5 hours in 3 months before enrollment. Those who meet any of the above conditions are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Color Doppler flow parameters of neck vessels;Transcranial Doppler cerebral blood flow parameters;Risk of ASCVD over 10 years; | — |
Secondary
| Measure | Time frame |
|---|---|
| human morphology;glucose and lipid metabolism;arteriosclerosis test;muscular strength;Muscle-brain crosstalk correlation factors;muscle mass;hemorheology indexes;muscle morphology;inflammatory markers; | — |
Countries
China
Contacts
Public ContactLianHua Yin
The Second People's Affiliated Hospital of Fujian University of Traditional Chinese Medicine
Outcome results
None listed