insomnia disorder
Conditions
Interventions
High-altitude Non-insomnia Immigrant Group:High altitude exposure and no insomnia
High-altitude insomnia Immigrant Group:High altitude exposure and insomnia
Lowland Control Han Group:Lowland Control
High-altitude Tibetan Group:High altitude exposure and ethnicity
Sponsors
Institute of Basic Research in Clinical MedicineChina Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. High-altitude immigrant Han group was included in the age group of 18-55 years old; young Han Chinese males whose original place of residence was below 1000m above sea level and who have now migrated to areas with an average elevation of 3800-4000m or 4500m above sea level and who have lived at the current elevation for more than 6 months who have adapted to plateau life and do not feel unwell; those who have not been to the plateau area before and do not have a history of cardiopulmonary and other basic diseases. 2. High-altitude Tibetan group included young Tibetan males aged 18-55 years who had lived at an altitude of more than 3000 meters above sea level for more than 6 months had adapted to highland life and were not unwell; there was no history of cardiac or pulmonary diseases. 3. Lowland Control group included young Han Chinese males aged 18-55 years who lived at an altitude of <1000 m and did not have a history of long-term residence at an altitude of 2000 m or higher.
Exclusion criteria
Exclusion criteria: 1. Excluding chronic diseases abnormalities in liver and kidney function electrocardiogram chest X-ray abdominal ultrasound, etc.; 2. Recent history of trauma and surgery fever inflammation and other conditions that may affect the test results (e.g. poor physical condition consumption of alcohol medication, etc.); 3. and visual, auditory, and speech impairments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differential proteins;Differential metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| age;gender;Nation;Altitude of residence; | — |
Countries
China
Contacts
Public ContactRui Xu
Institute of Basic Research in Clinical MedicineChina Academy of Chinese Medical Sciences
Outcome results
None listed