Joint and soft tissue injuries
Conditions
Interventions
Gushang Liniment group:At 48 hours post-injury Gushang Liniment (dosage adjusted per lesion size) was applied topically to the affected site every 10 minutes (3–4 times daily) alongside standard care.
Conventional treatment group:Oral imrecoxib (0.1 g/capsule BID).
Jingushang Spray group:At 48 hours post-injury Jingushang Spray (dosage adjusted per lesion size) was applied topically to the affected site every 10 minutes (3–4 times daily) alongside standard care.
Sponsors
the 71st Group Army Hospital of the Chinese PLA Army
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients meeting the diagnostic criteria for limb soft tissue injuries including sprains of the knee ankle and wrist joints presenting with localized pain swelling and restricted range of motion. Eligible participants were aged 18–60 years with no prior use of oral or topical pharmacotherapy or alternative treatments. Exclusion of individuals with neurovascular impairment cardiovascular hepatic renal or hematopoietic disorders as well as psychiatric conditions tuberculosis or malignancies. All participants provided written informed consent prior to enrollment.
Exclusion criteria
Exclusion criteria: Exclusion criteria comprised: age 60 years; history of severe cardiac hepatic splenic pulmonary or renal dysfunction; pregnancy or lactation; non-adherence to prescribed treatment regimens; inability to assess efficacy due to incomplete data or confounding factors; occurrence of severe adverse events (SAEs) complications or physiological alterations necessitating trial discontinuation; voluntary withdrawal or premature termination of treatment or follow-up assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bruising elimination time;White blood cell differential;Mobility status;White blood cell (WBC) count;Red blood cell (RBC) count;Serum c-reactive protein (CRP) level;Joint function grading;Bruising severity;Pain score (NRS);Swelling severity;Pain elimination time;Swelling elimination time;Platelet count;Serum erythrocyte sedimentation rate (ESR); | — |
Countries
China
Contacts
Public ContactYang Yang
the 71st Group Army Hospital of the Chinese PLA Army
Outcome results
None listed