Chronic airway inflammation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: People with high exposure to PM2.5 1) 18-65 years old continuous on-the-job for = 2 years working = 6 hours per day 2) No hormones and traditional Chinese medicine preparations were taken in the past 3 months 3) Agree to join the study and sign the informed consent form Low exposed population The staff in the subway office (air conditioning device equipped with PM2.5 filter) are the same as the highly exposed population. 4.2 Exclusion Criteria 1) PM2.5 mask wearer 2) Smoker history 3) Patients allergic to seafood and traditional Chinese medicine 4) Pregnant and lactating patients
Exclusion criteria
Exclusion criteria: 1) PM2.5 mask wearer 2) Smoker history 3) Patients allergic to seafood and traditional Chinese medicine 4) Pregnant and lactating patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal flora;Serum Th1/Th2 cells;COOP/WONCA Functional Scale;Quality of Life Evaluation Form;Balance index (IFN-?/IL-4) and secreted factor (IFN-?, IL-4, IL-12, IL-6) levels; | — |
Countries
China
Contacts
Chengdu University of Traditional Chinese Medicine