Knee Osteoarthritis
Conditions
Interventions
conventional electroacupuncture group:For the more painful side (acute phase) needles were inserted at Zusanli (ST36) Dubi (ST35) Neixiyan (EX-LE4) Xuehai (SP10) Liangqiu (ST34) Yanglingquan (GB34) Yi
the sham opposing electroacupuncture group:The more painful side received real acupuncture (same points as the opposing electroacupuncture group), while the less painful side received sham needling at
the opposing electroacupuncture group:On the more painful side , needles were inserted at Zusanli (ST36), Dubi (ST35), Neixiyan (EX-LE4), Xuehai (SP10), Liangqiu (ST34), Yanglingquan (GB34), Yinlingqu
Sponsors
Chongqing Thirteenth People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Meeting the diagnostic criteria for knee osteoarthritis (KOA): Recurrent knee pain within the past month along with at least two of the following four conditions: age = 40 years; morning stiffness lasting = 30 minutes; crepitus (sound or sensation of bone friction) during knee movement; and radiographic evidence (standing or weight-bearing X-ray) showing joint space narrowing subchondral sclerosis and/or cystic changes and osteophyte formation at the joint margins; 2.Age =40 years with knee pain lasting =6 months; 3.Kellgren-Lawrence (K-L) radiographic grade II or III:Grade II: Definite osteophytes with possible joint space narrowing;Grade III: Moderate osteophytes definite joint space narrowing and sclerotic changes; 4.Numeric Rating Scale (NRS) score =4 (range: 0–10 higher scores indicate worse pain); 5.Willingness to participate and signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Significant knee inflammation such as marked joint swelling or moderate/large joint effusion; 2.Knee pain caused by other diseases (e.g. rheumatoid arthritis infectious arthritis); 3.History of knee replacement surgery or scheduled for joint replacement; 4.Arthroscopy within the past 12 months or intra-articular injection within the last 6 months; 5.Acupuncture treatment within the past 3 months; 6.Severe acute/chronic systemic diseases or psychiatric disorders including:Cardiac: heart failure severe arrhythmia angina pectoris;Renal/hepatic: kidney/liver failure;Others: malignancy COPD dementia schizophrenia etc.; 7.Coagulation disorders or metal implants (e.g. pacemakers deep brain stimulators); 8.Needle phobia or metal allergy; 9.Pregnancy or lactation; 10.Participation in other clinical trials within 3 months or ongoing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in scores from baseline to week 8 on the Chinese version of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC Pain Subscale Score;WOMAC Stiffness Subscale Score;GPS;KOOS;WOMAC Physical Function Subscale Score;Lequesne Index;VAS;NRS;SF-36; | — |
Countries
China
Contacts
Public ContactTingting Luo
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed