Parkinson's disease
Conditions
Interventions
TA Group:Needling
Sponsors
Hospital of Chengdu University of TCM
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with idiopathic PD according to the Movement Disorder Society Clinical Diagnostic Criteria for PD (2015) with stable physical condition; (2) Male or female aged 40 and 80 years.; (3) Hoehn and Yahr stage 1.0 to 2.5 meeting the definition of early-stage PD; (4) Disease duration =3 years with a stable dosage of anti-Parkinsonian medications for at least 3 months before enrollment and expected to remain stable throughout the intervention and follow-up period (minimum 6 months); (5) Voluntary participation with signed informed consent; (6) Demonstrates good compliance and is able to complete the 12-week intervention and 1-year follow-up including all planned study visits. Note: Participants must meet all criteria to be eligible.
Exclusion criteria
Exclusion criteria: (1) Atypical or secondary parkinsonism or any serious cardiovascular cerebrovascular hepatic renal (creatinine clearance <30 mL/min) hematologic oncologic or other neurological disorders (e.g. stroke epilepsy); (2) Diagnosis of severe psychiatric disorders (e.g. schizophrenia major depressive disorder) or evidence of cognitive hearing or visual impairment that may interfere with assessments; (3) Untreated or uncontrolled physical pain that may affect gait such as severe osteoarthritis or lumbar disc herniation. (4) Use of medications affecting motor or neurological function (e.g. antipsychotics anticholinergics benzodiazepines) within 30 days prior to enrollment except for stable-dose anti-Parkinsonian drugs. (5) Participation in another clinical trial within 30 days before screening. (6) Presence of skin diseases affecting acupuncture sites such as psoriasis or local infections. (7) History of allergic reactions to acupuncture or severe needle phobia. Note: Meeting any criterion results in exclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite Clinical Motor Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| non-motor symptoms scale;6-Minute Walk Test 6MWT;Purdue Pegboard Test Score;Clinical Global Impression Scale;39-Item Parkinson's Disease Questionnaire;Timed Up and Go Test;Levodopa Equivalent Daily Dose;(MDS Unified Parkinson Disease Rating Scale); | — |
Countries
China
Contacts
Public ContactLiang Fanrong
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed