lung cancer
Conditions
Interventions
Treatment group:Modified Huangqi Guizhi Wujufu Decoction combined with foot and hand bloodletting
Control group:mecobalamin tablet
Sponsors
Shanxi Provincial Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients whose lung cancer has been confirmed by pathology or cytology; 2) Patients aged 18-80 years old, with no gender restrictions; 3) Patients with KPS score = 60 and expected survival period of no less than 3 months; 4) Patients who developed peripheral neuropathy after receiving paclitaxel (albumin-bound) treatment; 5) Patients without major organ dysfunction of the major systems and without cardiovascular or cerebrovascular complications; 6) All four limbs' skin is intact; 7) Patients who can understand the situation of this study, voluntarily accept traditional Chinese medicine treatment, and have good compliance with questionnaire survey.
Exclusion criteria
Exclusion criteria: 1) Patients with platelet count lower than 60×109/L or prothrombin time greater than 16 seconds who are prone to bleeding; 2) Patients with symptoms related to nerve compression caused by brain metastasis, or peripheral nerve damage due to tumor compression; 3) Patients with previous peripheral neuropathy, such as neurological diseases, orthopedic-related diseases, or peripheral nerve damage caused by circulatory disorders; 4) Patients with a history of drug contact allergy or with skin lesions on hands and feet (such as eczema); 5) Patients who cannot cooperate with treatment; 6) Pregnant or lactating women; 7) Patients who have participated in other clinical trials currently or within 4 weeks; 8) Patients with allergic constitution and prone to drug allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EORTCQLQ-CIPN20; | — |
Secondary
| Measure | Time frame |
|---|---|
| Psychological State Rating Scale;NCI-CTCAE V5.0;FACT/GOG-Ntx subscale;Traditional Chinese Medicine Syndrome Score;VAS score; | — |
Countries
ZHONGGUO
Contacts
Public ContactLi Xiaoli
Shanxi Provincial Academy of Traditional Chinese Medicine
Outcome results
None listed