Gout
Conditions
Interventions
Western Medicine Section:Allopurinol 0.1 g/time, qd+Yunpi Huashi Granule Simulator 1 pack, bid
Integrated Traditional Chinese and Western Medicine Group:Allopurinol 0.1 g/time qd+Yunpi Huashi Granule 1 pack bid
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Those who meet the classification of gout and the diagnosis of refractory gout; 2) Those who meet the diagnosis of spleen deficiency and dampness-heat accumulation syndrome; 3) Age = 18 years old and = 65 years old, male or female; 4) The drugs that have not been used in the first 15 days and affect the observation of this test are selected; (5) Patients were informed and consented to participate in the study.
Exclusion criteria
Exclusion criteria: 1) Those with severe joint deformities multiple tophi all over the body with local ulceration; 2) Severe lesions of important organs or mental illness; 3) People who are allergic to or contraindicated from the use of the drugs involved in the study protocol; 4) Pregnant or breastfeeding patients; 5) HLA-B-5801 gene positive patients were clearly detected; 6) The investigator believes that the requirements for admission to this clinical trial are not met.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood uric acid fluctuation; | — |
Secondary
| Measure | Time frame |
|---|---|
| erythrocyte sedimentation rate;TCM syndrome score;C-reactive protein;Blood uric acid value;tongue coating score;Tophi reduction rate;Number of tophus;Blood uric acid compliance rate;Urate of Urate Crystal Deposition by Energy Spectrum CT; | — |
Countries
China
Contacts
Public ContactHailong Wang
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Outcome results
None listed