Atherosclerosis
Conditions
Interventions
Intervention group:Shenling Baigui Granules (consisting of 15g Codonopsis pilosula 15g Epimedium brevicornu 15g Phellodendron amurense 15g Angelica sinensis 10g Ligusticum chuanxiong 15g Paeonia lacti
Sponsors
Guang'anmen Hospital Jinan Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Meets the diagnostic criteria for lower limb arteriosclerotic occlusive disease (Rutherford Stage 0–1) or atherosclerotic carotid artery disease; voluntarily participates in the study and signs an informed consent form; aged 18–75 years.
Exclusion criteria
Exclusion criteria: (1) Patients who have allergic reactions or other adverse reactions to the trial medication; (2) Patients with blood disorders such as coagulation dysfunction anemia or platelet abnormalities; (3) Patients with a history of bleeding disorders in the past three months; (4) Patients with conditions at high risk of major bleeding such as peptic ulcers malignant tumors esophageal varices arteriovenous malformations or vascular aneurysms; (5) Patients with severe comorbidities such as diabetes heart failure cerebral hemorrhage or abnormal liver or kidney function; (6) Patients with inflammatory vascular diseases such as thromboangiitis obliterans Takayasu arteritis or Raynaud's syndrome; (7) Pregnant or breastfeeding women; (8) Patients with psychiatric disorders; (9) Patients whom the investigator deems to have poor compliance and are unlikely to cooperate with the treatment; (10) Patients with incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum TNF-a level; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipid level;Serum VCAM-1 level;Serum P-selectin level;Serum IL-1ß level;Serum ICAM-1 level;Serum I?Ba level;Serum E-selectin level;Serum NF-?B p65 level; | — |
Countries
China
Contacts
Public ContactYutao WANG
Guang'anmen Hospital Jinan Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed