knee osteoarthritis
Conditions
Interventions
test group:Tongdu Tiaoshen acupuncture
control group:sham acupuncture
Sponsors
The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1)In line with the diagnostic criteria of knee osteoarthritis in the osteoarthritis diagnosis and treatment guidelines ( 2018 edition ) :repeated knee pain in the last month;X-ray films (standing or weight-bearing position ) showed narrowing of the joint space subchondral bone sclerosis and / or cystic degeneration and osteophyte formation;at least 50 years old;morning stiffness time = 30min;bone friction sound ( sense ) ;meet the diagnostic criteria 1 + ( 2345 of any 2 ). (2)between the ages of 50 and 60. (3)Initial central sensitization scale score = 40 points. (4)Analgesic drugs or hormone therapy were not performed in the last month; (5)Agree to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1)Those who resisted acupuncture treatment or could not tolerate acupuncture treatment. (2)Pregnant ; combined with other types of arthritis such as gouty arthritis rheumatoid arthritis psoriatic arthritis infectious arthritis ; combined with other diseases that can lead to decreased muscle strength or muscle atrophy such as cerebrovascular disease peripheral nerve disease acute fracture and other diseases. (3) Those who were taking opioids non-steroidal anti-inflammatory drugs hormone drugs and could not stop because of other diseases. (4) Those combined mental illness or cognitive dysfunction can not fully cooperate with the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale;The Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-hydroxytryptamine;The tenderness threshold around knee joint;brain-derived neurotrophic factor;central sensitization inventory;30s chair-stand test;40m fast-paced walk test;Interleukin-1ß;Tumor necrosis factor alpha; | — |
Countries
China
Contacts
Public ContactXiahai Zheng
The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed