Tic Disorders
Conditions
Interventions
PNT + SIT Group:Press needle therapy applied to standardized auricular points plus sensory integration training 3x/week for 12 weeks
Medication Control Group:Oral tiapride hydrochloride, titrated up to 600 mg/day.
SIT Group:Sensory integration training 3x/week for 12 weeks only
Sponsors
Luohu District Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 18 Years
Inclusion criteria
Inclusion criteria: Children aged 3-18 years were eligible if they met the following inclusion criteria: (1) a dual-confirmed diagnosis of TD based on DSM-5 criteria and TCM classification (e.g. "slow convulsive wind" or "liver wind syndrome"); (2) mild-to-moderate symptoms defined as Yale Global Tic Severity Scale (YGTSS) =35); (3) normal hepatic renal and neurophysiological function at baseline; (4) no prior treatment for TD or completion of a =2-week washout period; and (5) provision of informed consent and willingness to adhere to the study protocol.
Exclusion criteria
Exclusion criteria: Exclusion criteria included: (1) secondary tic-like symptoms due to organic brain disorders; (2) comorbid neurodevelopmental disorders or major organ dysfunction; (3) known allergies to stainless steel or tiapride hydrochloride; and (4) participation in other clinical trials during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Yale Global Tic Severity Scale (YGTSS) from baseline to Week 12;Traditional Chinese medicine syndrome scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events;Clinical response rate; | — |
Countries
China
Contacts
Public ContactPeng Fan
Luohu District Hospital of Traditional Chinese Medicine
Outcome results
None listed