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The effect of Liuhe Pill in the treatment of pain and swelling after orthognathic surgery: a randomized controlled trial

The effect of Liuhe Pill in the treatment of pain and swelling after orthognathic surgery: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001267
Enrollment
Unknown
Registered
2025-06-26
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental and maxillofacial deformities

Interventions

Control Group:Placebo Plaster: The control group patients were given a placebo simulating the six-ingredient pill plaster, with the application method, frequency, and of treatment exactly the same as
Intervention group:Six-in-one ointment for external use: Application site: From the first day after surgery, apply the six-in-one ointment the red, swollen, hot, and painful areas of the face, avoidin

Sponsors

West China Hospital of StomatologySichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1)Patients with intact facial skin after orthognathic surgery;2)Aged =18 years old;3)No other severe organ diseases;4)After the purpose and content of the study, the patients and their families signed the informed consent.

Exclusion criteria

Exclusion criteria: 1)Persons with skin ulceration, infection, or wounds in the facial area;2)Pregnant or lactating women;3)Patients with organ failure as liver or kidney failure, and cardiovascular dysfunction;4)Patients with allergic constitution or allergic to multiple drugs;5)Patients with mental disorders.

Design outcomes

Primary

MeasureTime frame
Postoperative inflammatory marker levels;Postoperative facial swelling;pain;

Secondary

MeasureTime frame
Postoperative functional recovery;Adverse drug reaction;Patient satisfaction;Complications;

Countries

China

Contacts

Public ContactBi Xiaoqin

West China Hospital of StomatologySichuan University

hxbxq@163.com+86 135 4116 8806

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026