Chemotherapy-induced constipation related to lung cancer
Conditions
Interventions
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Confirmed by pathological histology or cytology examination diagnosed as patients with malignant lung tumors; (2) Meet the diagnostic criteria for constipation in Western medicine and constipation (deficiency constipation) in traditional Chinese medicine; (3) After clinical diagnosis and assessment patients who are scheduled to receive chemotherapy treatment in the oncology department and whose chemotherapy plan contains platinum-based drugs; (4) Age = 18 and = 80 years old gender not limited with an expected survival period of = 3 months; (5) KPS (Functional Status Karnofsky Rating Scale) score = 70 points; (6) The patient can cooperate in evaluating constipation symptoms and after examination there is no severe liver or kidney dysfunction and no intestinal lesions; (7) The skin at the abdominal massage site is intact; non-fasting patients; (8) The patient is conscious and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with constipation caused by other reasons (such as local lesions etc.) those with acute intestinal obstruction habitual constipation or those using antidepressants; (2) Patients with gastrointestinal bleeding or infections in other parts or organs as well as those in the middle or late stage who cannot tolerate treatment; (3) Patients after intestinal fistula surgery or after total resection of the rectum (>50%); (4) Patients with severe primary diseases such as cardiovascular liver kidney hematopoietic system diseases and those with mental disorders; (5) Patients participating in any other clinical studies for preventing or treating constipation during chemotherapy; (6) Patients using opioid analgesics such as morphine during chemotherapy; (7) Patients who self-report being allergic to adjuvants; (8) Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total effective rate after one week of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time T1 at which the treatment took effect for the two groups of patients;PAC-SYM;Interval time for defecation T2;PAC-QOL; | — |
Countries
china
Contacts
Public Contactshen yonghong
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Outcome results
None listed