Duration of Non-Hypoxic Apnoea during Anesthesia Induction Period
Conditions
Interventions
Sponsors
Northern Jiangsu People's HospitalAffiliated to Yangzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 18-65 years old; ASA (American Society of Anesthesiologists) physical status classification I-II; No history of acupuncture or transcutaneous electrical acupoint stimulation (TEAS) treatment within the past 6 months; Clear consciousness autonomous capacity and ability to communicate and cooperate; No history of respiratory tract infection chronic cough with sputum or gastric acid reflux preoperatively; Willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Severe cardiovascular pulmonary or neurological diseases; History of thoracotomy pulmonary surgery or neck surgery; Blood or endocrine system dysfunction; Severe hepatic or renal dysfunction; History of drug abuse or alcoholism; Allergy to TEAS electrode pads; Psychiatric disorders; Poor comprehension and inability to cooperate with the trial; Lactating or pregnant women; Participation in other clinical trials; Local skin damage or infection at acupoint sites; Individuals with implanted temporary/permanent pacemakers or other electronic devices; patients with electrocardiogram (ECG)-confirmed atrioventricular block; Intubation time > 1 minute or intubation attempts > 2 times; Preoperative transcutaneous oxygen saturation < 92% or arterial partial pressure of oxygen < 60 mmHg (1 mmHg = 0.133 kPa).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the duration of non-hypoxic apnoea during anesthesia induction period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Record the peak airway pressure (Ppeak), plateau airway pressure (Pplat), and dynamic lung compliance (Cdyn) at 2 minutes after mechanical ventilation.;Record the heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) at the following four time points: T0: after entering the room and breathing room air; T1: 3 minutes after preoxygenation; T2: after successful endotracheal intubation; T3: when SpO2 drops to 92% or the safe apneic duration reaches 480 seconds.;Record the arterial partial pressure of oxygen and arterial partial pressure of carbon dioxide at time points T0 ,T1, and T3.;The occurrence of adverse reactions during the anesthesia process;Record the SpO2 values at time points T0 and T1, the minimum SpO2 value (the lowest value before SpO2 rebounds), the reoxygenation time ?T (the time from the start of mechanical ventilation to when SpO2 reaches 98%), and the number of cases where the safe apneic duration reaches 480 seconds.; | — |
Countries
China
Contacts
Public ContactCunjin Wang
Northern Jiangsu People's Hospital Affiliated to Yangzhou University
Outcome results
None listed