Lower Extremity Arteriosclerosis Obliterans
Conditions
Interventions
control group:Fuyuan Tongluo Decoction-Matched Placebo
test group:Fuyuan Tongluo Decoction
Sponsors
Shuguang hospital affiliated to Shanghai university of traditional Chinese medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the ASO diagnostic criteria. (2) Those whose Rutherford classification belongs to grade I-3 to III. (3) Those who are recognized as blood stasis type in Chinese medicine. (4) 40 < age = 80 years old gender is not limited (for women of childbearing age a pregnancy urine test must be performed the pregnancy test must be negative and the patient must not be breastfeeding at the time of the screening visit). (5) Patients with good compliance and ability to cooperate with treatment and observation.
Exclusion criteria
Exclusion criteria: (1) Those with acute or severe limb ischemia such as lower extremity arterial thrombosis and lower extremity arterial embolism. (2) Those who suffer from other inflammatory vascular diseases such as thromboembolic vasculitis and polyarteritis. (3) Those with other diseases affecting activities such as lower limb shutdown lesions and neuropathy. (4) Patients with severe cardiac cerebral hepatic or renal insufficiency or (and) history of major surgery. (5) Pregnant women nursing mothers and special groups of people with combined mental illness. (6) Those who have allergic reactions to the Chinese medicines used or other adverse reactions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain-Free Walking Time;Maximum Walking Time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lipid Indicators;SF-36 Quality of Life Score;Incidence of ulcers, gangrene and amputations;Chinese Medicine Criteria Score;Walking Impairment Questionnaire;Fibrinogen;Buerger's Test;plasma viscosity;Tumor Necrosis Factor a;Ankle–Brachial Index;high sensitive C Reactive Protein;Restenosis Rate in Patients with Prior Endovascular Intervention;Capillary Refill Test; | — |
Countries
China
Contacts
Public ContactLiu Guobin
Shuguang hospital affiliated to Shanghai university of traditional Chinese medicine
Outcome results
None listed