Advanced non-small cell lung cancer
Conditions
Interventions
Combined group (Yanghe decoction +TP regimen chemotherapy):Patients in the combination group started taking Yanghe Tang 7 days before chemotherapy and continued until the end of chemotherapy. Yanghe T
Control group (placebo +TP chemotherapy):Paclitaxel 175mg/m2 (or docetaxel 75mg/m2) plus cisplatin 75mg/m2 was given every 3 weeks for 4 cycles. In the course of chemotherapy the dose of chemotherapy
Sponsors
Gansu University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with histologically or cytologically confirmed stage ?B-? NSCLC; Aged between 18-75 years; The expected survival time is more than 3 months; It met the diagnostic criteria of Yang deficiency and toxin knot type in the "Guidelines for the Diagnosis and Treatment of Lung Cancer with Integrated Traditional Chinese and Western Medicine" that is the patient had typical symptoms of Yang deficiency (such as fear of cold and cold limbs waist and knee soreness etc.) and symptoms of toxin knot (such as cough bloody sputum chest pain etc.).
Exclusion criteria
Exclusion criteria: Non-small cell lung cancer patients with unclear TNM staging according to the 8th edition of the Union for International Cancer Control; Patients who survived less than 1 year after diagnosis; Patients with incomplete data; Patients with concomitant tumors of other systems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FPS;ORR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Integral Evaluation;10/10000 Peripheral blood T cell subpopulations;Cold Fear Score Assessment;PARP1 activity;Serum butyric acid;Mitochondrial ATP; | — |
Countries
CHINA
Contacts
Public ContactZhuZhongbo
Gansu University of Chinese Medicine
Outcome results
None listed