polycystic ovary syndrome
Conditions
Interventions
treatment group:Letrozole intervention and ovulation monitoring are the same as control group. After confirming ovulation Shoutai Sijunzi granules. Performe pregnancy diagnosis during the 12th to 14t
control group:Take letrozole tablets from the 2nd day to the 5th day after menstruation or progesterone withdrawal bleeding. Ask subjects to have sex regularly. After confirming ovulation Chinese me
Sponsors
First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.PCOS patients with fertility requirements confirmed diagnosis according to the revised Rotterdam criteria and Chinese diagnosis and treatment guide for PCOS in 2018; 2.TCM syndrome differentiation of PCOS belongs to deficiency of spleen and kidney pattern; 3.Chinese women aged from 20 to 40 years; 4.Owing bilateral ovaries and FSH < 10mIU/L; 5.The husband semen is normal; 6.Presents bilateral or unilateral patency; 7.Informed and consented to participate in the study.
Exclusion criteria
Exclusion criteria: 1.There are obvious factors affecting embryo implantation; 2.Other causes of hyperandrogenism or ovulation disorders; 3.Have taken hormone medications or medications that affect insulin sensitivity within 3 months; 4.Within 6 weeks of pregnancybreastfeedingor post-abortion; 5.One partner of couples with chromosomal abnormality; 6.Spontaneous abortion =2 or more times.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The early abortion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;Serum glucose and lipid metabolism indicators;Ovulation rate;Serum hormone indicators;Pregnancy rate;Endometrial blood perfusion;The usage rate of fetus-preserving drugs;Safety indicators;Adverse pregnancy rate; | — |
Countries
China
Contacts
Public ContactLiu Hua
First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed